Update therapeutic range min/max values no longer mandatory

src/components/settings.tsx

@@ -394,11 +394,12 @@ const Settings = ({
                       min={0}
                       max={500}
                       placeholder={t('min')}
-                      required={true}
+                      required={false}
-                      error={!!therapeuticRangeError || !therapeuticRange.min}
+                      error={!!therapeuticRangeError}
-                      errorMessage={formatText(therapeuticRangeError || t('errorTherapeuticRangeMinRequired') || 'Minimum therapeutic range is required')}
+                      errorMessage={formatText(therapeuticRangeError)}
                       showResetButton={true}
                       defaultValue={defaultsForT.therapeuticRangeMin}
+                      allowEmpty={true}
                     />
                     <span className="text-muted-foreground">-</span>
                     <FormNumericInput
@@ -409,11 +410,12 @@ const Settings = ({
                       max={500}
                       placeholder={t('max')}
                       unit="ng/ml"
-                      required={true}
+                      required={false}
-                      error={!!therapeuticRangeError || !therapeuticRange.max}
+                      error={!!therapeuticRangeError}
-                      errorMessage={formatText(therapeuticRangeError || t('errorTherapeuticRangeMaxRequired') || 'Maximum therapeutic range is required')}
+                      errorMessage={formatText(therapeuticRangeError)}
                       showResetButton={true}
                       defaultValue={defaultsForT.therapeuticRangeMax}
+                      allowEmpty={true}
                     />
                   </div>
                 </div>

src/components/simulation-chart.tsx

@@ -76,6 +76,11 @@ const SimulationChart = React.memo(({
   const containerRef = React.useRef<HTMLDivElement>(null);
   const { width: containerWidth } = useElementSize(containerRef, 150);
 
+  // Guard against invalid dimensions during initial render
+  const yAxisWidth = 80;
+  const minContainerWidth = yAxisWidth + 100; // Minimum 100px for chart area
+  const safeContainerWidth = Math.max(containerWidth, minContainerWidth);
+
   // Track current theme for chart styling
   const [isDarkTheme, setIsDarkTheme] = React.useState(false);
 
@@ -96,9 +101,8 @@ const SimulationChart = React.memo(({
     return () => observer.disconnect();
   }, []);
 
-  // Y-axis takes ~80px, scrollable area gets the rest
+  // Calculate scrollable width using safe container width
-  const yAxisWidth = 80;
+  const scrollableWidth = safeContainerWidth - yAxisWidth;
-  const scrollableWidth = containerWidth - yAxisWidth;
 
   // Calculate chart width for scrollable area
   const chartWidth = simDays <= dispDays
@@ -106,7 +110,7 @@ const SimulationChart = React.memo(({
     : Math.ceil((scrollableWidth / dispDays) * simDays);
 
   // Use shorter captions on narrow containers to reduce wrapping
-  const isCompactLabels = containerWidth < 640; // tweakable threshold for mobile
+  const isCompactLabels = safeContainerWidth < 640; // tweakable threshold for mobile
 
   // Precompute series labels with translations
   const seriesLabels = React.useMemo<Record<string, { full: string; short: string; display: string }>>(() => {
@@ -446,6 +450,15 @@ const SimulationChart = React.memo(({
     );
   }, [seriesLabels]);
 
+  // Don't render chart if dimensions are invalid (prevents crash during initialization)
+  if (chartWidth <= 0 || scrollableWidth <= 0) {
+    return (
+      <div ref={containerRef} className="flex-grow w-full flex flex-col overflow-y-hidden items-center justify-center text-muted-foreground">
+        <p>{t('loadingChart', { defaultValue: 'Loading chart...' })}</p>
+      </div>
+    );
+  }
+
   // Render the chart
   return (
     <div ref={containerRef} className="flex-grow w-full flex flex-col overflow-y-hidden">
@@ -625,20 +638,20 @@ const SimulationChart = React.memo(({
                 />
               );
             })}
-            {showTherapeuticRange && (chartView === 'damph' || chartView === 'both') && (
+            {showTherapeuticRange && (chartView === 'damph' || chartView === 'both') && therapeuticRange.min && !isNaN(parseFloat(therapeuticRange.min)) && (
               <ReferenceLine
-                y={parseFloat(therapeuticRange.min) || 0}
+                y={parseFloat(therapeuticRange.min)}
-                label={{ value: t('refLineMin'), position: 'insideTopLeft' }}
+                label={{ value: t('refLineMin'), position: 'insideBottomLeft', style: { fontSize: '0.75rem', fontStyle: 'italic', fill: CHART_COLORS.therapeuticMin } }}
                 stroke={CHART_COLORS.therapeuticMin}
                 strokeDasharray="3 3"
                 xAxisId="hours"
                 yAxisId="concentration"
               />
             )}
-            {showTherapeuticRange && (chartView === 'damph' || chartView === 'both') && (
+            {showTherapeuticRange && (chartView === 'damph' || chartView === 'both') && therapeuticRange.max && !isNaN(parseFloat(therapeuticRange.max)) && (
               <ReferenceLine
-                y={parseFloat(therapeuticRange.max) || 0}
+                y={parseFloat(therapeuticRange.max)}
-                label={{ value: t('refLineMax'), position: 'insideTopLeft' }}
+                label={{ value: t('refLineMax'), position: 'insideTopLeft', style: { fontSize: '0.75rem', fontStyle: 'italic', fill: CHART_COLORS.therapeuticMax } }}
                 stroke={CHART_COLORS.therapeuticMax}
                 strokeDasharray="3 3"
                 xAxisId="hours"

src/hooks/useElementSize.ts

@@ -38,18 +38,26 @@ export function useElementSize<T extends HTMLElement>(
     const element = ref.current;
     if (!element) return;
 
-    // Set initial size
+    // Set initial size (guard against 0 dimensions)
+    const initialWidth = element.clientWidth;
+    const initialHeight = element.clientHeight;
+
+    if (initialWidth > 0 && initialHeight > 0) {
       setSize({
-      width: element.clientWidth,
+        width: initialWidth,
-      height: element.clientHeight,
+        height: initialHeight,
       });
+    }
 
     // Use ResizeObserver for efficient element size tracking
     const resizeObserver = new ResizeObserver((entries) => {
       for (const entry of entries) {
         const { width, height } = entry.contentRect;
+        // Guard against invalid dimensions
+        if (width > 0 && height > 0) {
           setSize({ width, height });
         }
+      }
     });
 
     resizeObserver.observe(element);